WebApr 18, 2013 · Bio-Synthesis, Inc. – Custom Peptide Synthesis, Custom Antibody ... WebMay 18, 2024 · Two GapmeR were designed: one to target the WBP1 sequence and a scrambled version of the same sequence used as a negative control. The sequence that targeted WBP1 (termed anti-WBP1) was: 5’- AGGCGAAGGTCAAGCA -3’. The sequence for the scrambled negative control was 5’-GCAGCGTACAAGGAAG-3’.
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WebAntisense LNA GapmeR in vivo Large Scale: high-quality, animal-grade LNA GapmeRs available in a range of scales with various purification and labeling options. Antisense … WebApr 16, 2024 · Both Gapmers significantly blunted the cAMP-dependent increase of ADEPTR in hippocampal neurons (untransfected + FSK: 7.5 ± 0.91, scrambled Gapmer + FSK: 6.8 ± 0.73, Gapmer1 + FSK: 3.7 ± 0.67, and Gapmer2 + FSK: 1.5 ± 0.47, N = 4 to 6 per group, P < 0.05, one-way ANOVA and Tukey’s post hoc test) ( Fig. 2B, fig. S10, and table S2). is mathletics a game
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WebGapmeR-Wisper and GapmeR-Scrambled control A (Exiqon) were diluted in NaCl 0.9% isotonic solution to obtain the final exact concentration (5, 10, or 15 mg/kg) just before … WebAug 22, 2024 · (F) Transcript expression of Egr2 6 hr, 24 hr, and 48 hr post-injury using RNA from injured sciatic nerves treated with AS-RNA GapMers or scrambled GapMers. The results are presented as fold change of Egr2 transcript expression in AS-RNA-GapMer-treated nerves versus scrambled-GapMer-treated nerves. The experiment was repeated … WebJul 15, 2024 · The scramble-ASO has also PS-modified nucleotides surrounding an unmodified DNA-like “gap.” Electrostatic binding with Tat was performed by mixing Tat-CPP-(GRKKRRQRRR) (GeneScript, Piscataway, NJ, USA) with BGas- or scramble-gapmer to obtain a final concentration of 200:10 μM ratio, respectively . After 2 h incubation at 37°C ... is math left or right brained